16 feb 2015 the two seem to go hand in hand in the case of the new hepatitis c virus (hcv) cure named sofosbuvir, sold under the brand name sovaldi by; 16 may 2013 sofosbuvir plus peg in ter fer on alfa-2a and ribavirin in 327 patients with in a single-group study of sofosbuvir combined with peg in ter fer; 16 nov 2015 once-daily sofosbuvir;velpatasvir for 12 weeks provided high rates of sustained virologic response among both previously treated and; 1 jan 2014 sofosbuvir and other nucleotide inhibitors of the hcv rna polymerase exhibit a very high barrier to resistance development. 16 nov 2015 treatment with sofosbuvir;velpatasvir with or without ribavirin for 12 weeks and with sofosbuvir;velpatasvir for 24 weeks resulted in high rates; learn about the potential side effects of ledipasvir/sofosbuvir. 17 dec 2015 the present invention relates to a pharmaceutical composition containing the active ingredient sofosbuvir. 19 aug 2016 recently gilead released epclusa (sofosbuvir 400 mg/velpatasvir 100 mg), with the claim that it was the first pan-genotypic, single tablet; 9 may 2015 ledipasvir and sofosbuvir in patients with genotype 1 hepatitis c virus infection and compensated cirrhosis: an integrated safety and efficacy; jama. 19 nov 2015 ;we can say that daclatasvir plus sofosbuvir plus ribavirin for 12 or 16 weeks is a highly efficacious therapy for genotype 3;infected patients; sofosbuvir is a first-in-class nucleotide inhibitor of the nonstructural protein 5b ( ns5b, the hcv rna-dependent rna polymerase) that was approved by health ; sofosbuvir (gs-7977) belongs to a class of anti-hepatitis c virus (hcv) drugs called nucleotide analogues. 2 apr 2016 most sofosbuvir combinations are oral and interferon-free, and patients are eligible for pbs subsidy irrespective of treatment experience and; 3 aug 2016 sofosbuvir is one of a number of new direct-acting antiviral drugs revolutionising the care of people living with hepatitis c. 2 jun 2016 the fisherman;s doctor recommended treatment that included a drug called sofosbuvir. 2; comprehensive sofosbuvir portfolio, including molecular targets, moa, partnerships, milestones. 20 jul 2016 sofosbuvir ; 400 mg; velpatasvir ; 100 mg should not be used with epclusa, as it can lower levels of both sofosbuvir and velpatasvir. 20 nov 2015 the combination of sofosbuvir plus velpatasvir could treat hepatitis c genotypes 1, 2, 4, 5, and 6, reducing the need for tests and monitoring. 20 oct 2016 gilead announces svr12 rates from four phase 3 studies of a once-daily, fixed-dose combination of sofosbuvir, velpatasvir and; 27 may 2016 --epclusa is gilead;s third sofosbuvir-based treatment to receive a chmp positive opinion for the treatment of chronic hcv infection--.